Endocrine Abstracts

Treatment of hypoparathyroidism with vitamin D analogs and calcium does not restore normal physiologic regulation of calcium homeostasis in the bone and kidney and may lead to renal insufficiency due to progressive nephrocalcinosis. Replacement with PTH potentially addresses this problem but until recently, hypoparathyroidism was the only classic hormonal insufficiency state not treated with its missing hormone.Over the past two decades, we have evaluate...